Study were examined because of the three-means ANOVA having pairwise analysis followed closely by Tukey’s post hoc sample

Affiliations

The primary goal of this study was to analyze urinary Na + , K + and the Na + :K + excretion ratio, for associations with changes in systolic blood pressure (SBP) in participants from the DASH–Sodium trial during the initial screening period in which participants were consuming their regular diet without dietary intervention. The secondary goals of this study were to investigate: (a) the impact of the salt sensitivity of blood pressure on these responses and (b) the impact of the DASH–Sodium dietary intervention, which lowers SBP and increases dietary K + intake, on these potential associations. Our analysis reports that in the DASH–Sodium study cohort: (1) a daily excretion of <1 g K + /day is associated with elevated SBP, (2) urinary K + excretion of >1 g/day does not correlate with a reduction in SBP and, (3) a reduction in the urinary Na + :K + excretion ratio is not associated with lower SBP irrespective of the salt sensitivity of blood pressure. Collectively our data support the recent DRI recommendation not to propose a DRI for K + and suggest that further evidence is required to support the establishment of a Na + /K + excretion ratio that would reduce SBP in the general population.

Analytical parameters

Indicate SBP in line with urinary salt to help you potassium (Na + /K + ) removal ratio during the time of evaluation in accordance with fat reduction input out of Weight reduction Remedies for Prevent Blood pressure level (DASH) higher sodium (HS) and you may reduced salt (LS) diet for the (a) salt sensitive and painful (letter = 71), (b) sodium unwilling (letter = 119) individuals, viewpoints shown just like the indicate ± SD.

Significantly, we observed no association between the urinary Na + :K + ratio and SBP on the DASH HS or DASH LS dietary intervention in either SS (DASH HS R 2 = 0.04, DASH LS R 2 = 0.02) or SR (DASH HS R 2 = 0.04, DASH LS R 2 = 0.00002) participants (Fig. 5a, b). The DASH dietary intervention significantly increased the number of participants in both SS and SR groups with a urinary Na + :K sex dating service + ratio of <1 on both the HS and LS diet. However, the urinary Na + :K + had no impact on SBP within dietary intake groups (Fig. 6a, b). Further, when expressed as a frequency distribution histogram the change in SBP from the DASH HS to LS dietary intervention exhibits a profound leftward shift in the SS group compared to SR group (Fig. 7a). In contrast, the frequency distribution histogram for change in the urinary Na + :K + ratio from the DASH HS to LS dietary intervention shows no difference in the Gaussian curve and distribution between SS and SR participants (Fig. 7b).

Subsequent, several research has suggested that the blood pressure level avoidance evoked because of the K + intake tends to be dependent on weightloss Na + intake [twenty eight, 29]. In our research of your own Dash-Sodium dataset i observed zero organization that have urinary K + removal and you can SBP, into the patient testing see otherwise throughout Dashboard fat loss input whenever Na + intake was changed, indicating an independence of your ramifications of Na + and you may K + to the SBP contained in this studies. This new 2019 DRI Report determined that there is lack of proof towards the effects away from K + towards the blood pressure and you may didn’t introduce a beneficial DRI away from K + . Our very own investigation support the 2019 DRI Declaration and means that weightloss K + supplements may well not notably remove blood circulation pressure throughout the general inhabitants.

Conclusion

Stamler J, Rose G, Stamler R, Elliott P, Dyer Good, Marmot Meters. INTERSALT investigation results. Societal health insurance and health care implications. Blood pressure levels. 1989;–7.